Biography
Dr. Rachel (Rae) House earned her Ph.D. in molecular and cell biology from Van Andel Institute Graduate School and her B.S. in biology from Calvin College. During her graduate training, Rae identified metabolic vulnerabilities in NF1-deficient ER+ in breast cancer (Molecular Metabolism), developed a metabolomics method to minimize protein confounders (Nature Communications), and designed an open-source R-based software to analyze Seahorse energetics data (Bioinformatics). In 2024, she joined the lab of Dr. Evan Lien and secured an appointment to the VAI Cancer Epigenetics Training (CET) Program (award no. T32CA251066; PI: Peter A. Jones). The objectives of Rae’s postdoctoral research are to (i) map the identity and specificity and lipid uptake regulators in cancer and (ii) explore the spatiotemporal contribution of ketone-derived histone post-translational modifications to epigenetic regulation in cancer.